Getting Your Patient
Started With Upneeq ^®
(oxymetazoline hydrochloride ophthalmic solution), 0.1%

Simple, once-daily dosing ¹

	Step 1: Cut open foil wrapper and remove single-use vial
	Step 2: Apply 1 drop of Upneeq in each affected eye as directed, once a day Don’t touch eye with the tip of the vial or touch the tip of the vial to any other surface Throw the single-use vial away immediately after applying drops. Vials should not be re-used after opening

Patients who wear contact lenses should remove them before applying Upneeq eyedrops. Contact lenses can be put back in 15 minutes after applying Upneeq.

If more than one topical ophthalmic drug is being used, the drugs should be administered at least 15 minutes between applications.

For complete instructions on using Upneeq, please see the Instructions for Use section in the full Prescribing Information.

Storage requirements: Upneeq should be stored at 68°F-77°F (20°C-25°C) and should be protected from excessive heat.

Keep out of reach of children.

Modernizing prescription access

Upneeq is available for patients under your care for a consistent and uniform price. Treatment is a choice between you and your patient. RVL Pharmacy does not accept payments from insurance providers, therefore accessing Upneeq is free of traditional hassles such as Prior Authorizations, Step Edits, and Callbacks.

Upneeq is available exclusively through RVL Pharmacy. Our friendly and knowledgeable pharmacy staff will contact patients, process Upneeq prescriptions, and facilitate home delivery. Elevate your expectations for what prescription access can be with Upneeq.

	Step 1: Send patient’s prescription for Upneeq directly to RVL Pharmacy
	Step 2: Pharmacy contacts patient to review the prescription, collect payment, and answer any questions
	Step 3: Upneeq is shipped directly to the patient’s home or preferred destination within 2-4 days following payment

Prescribing Upneeq

All prescriptions should be sent directly to RVL Pharmacy

844-RVL-EYES

(844-785-3937)

For more information about the location and hours for RVL Pharmacy, click here.

RVL Pharmacy ships to patients everywhere in the Continental U.S.

RVL Pharmacy
2500 Main Street Extension, Suite 10
Sayreville, NJ 08872
Phone: 844-RVL-EYES (844-785-3937)
Fax: 844-567-3937

Eye Care Professionals: Send all Upneeq prescriptions and direct all questions to RVL Pharmacy in Sayreville, NJ.
Phone: 844-RVL-EYES (844-785-3937)

ePrescribe

Select RVL Pharmacy in your EMR:

Location

Sayreville, NJ
08872

NPI

1770193757

NCPDP

3157369

Fax Number

844-567-3937

Phone Number

844-RVL-EYES
(844-785-3937)

HCP FAQs

Get to know Upneeq a little better. Here are some commonly asked questions from HCPs interested in prescribing Upneeq to their patients.

How do I prescribe Upneeq?

UPNEEQ is exclusively available through RVL Pharmacy. All prescriptions should be sent directly to RVL Pharmacy.

There are three ways to prescribe Upneeq:

ePrescribe

Select RVL Pharmacy in your EMR:

Location

Sayreville, NJ
08872

NPI

1770193757

NCPDP

3157369

Fax Number

844-567-3937

Phone Number

844-RVL-EYES
(844-785-3937)

Click here to download the fax form.

How is Upneeq supplied?

Upneeq is available in a case of 30 individually foil-pouched single patient-use vials (NDC 73687-062-32). ¹

I have prescribed Upneeq to my patient. What’s next?

Once you ePrescribe, fax, or call in a prescription for Upneeq to RVL Pharmacy, the pharmacy will contact your patient via phone to confirm their information and collect credit card payment. Once payment is completed, RVL Pharmacy will ship Upneeq directly to the patient’s preferred address.

How can my patients pay for Upneeq?

When the prescription is ready, RVL Pharmacy will contact the patient directly, and the patient will be able to pay over the phone by credit card.

Does RVL Pharmacy accept insurance? What is the cost of Upneeq to my patient?

RVL Pharmacy does not accept payments from insurance providers. Upneeq is available directly to patients through a fully transparent pricing model outside of the insurance process.

How and when will my patient receive Upneeq?

Upneeq will be shipped directly to your patient’s preferred address. They should receive their prescription within 2-4 days after payment.

How do I prescribe refills of Upneeq to my patients?

Refills should be prescribed directly to RVL Pharmacy. Depending on the state your patient lives in, Upneeq will ship directly to the patient via RVL Pharmacy or KnippeRx.

What are the storage requirements for Upneeq?

Upneeq should be stored at 68°F to 77°F (20°C to 25°C) and should be protected from excessive heat. It should be kept out of the reach of children. ¹

RVL Pharmacy Resources for HCPs

RVL Pharmacy Fax Form

This downloadable form is designed for HCPs who wish to fax prescriptions of Upneeq directly to the RVL Pharmacy.

DOWNLOAD

EXPAND

COLLAPSE

INDICATION

UPNEEQ ^® (oxymetazoline hydrochloride ophthalmic solution), 0.1% is indicated for the treatment of acquired blepharoptosis in adults.

IMPORTANT SAFETY INFORMATION

WARNINGS AND PRECAUTIONS

Ptosis may be associated with neurologic or orbital diseases such as stroke and/or cerebral aneurysm, Horner syndrome, myasthenia gravis, external ophthalmoplegia, orbital infection and orbital masses. Consideration should be given to these conditions in the presence of ptosis with decreased levator muscle function and/or other neurologic signs.
Alpha-adrenergic agonists as a class may impact blood pressure. Advise UPNEEQ patients with cardiovascular disease, orthostatic hypotension, and/or uncontrolled hypertension or hypotension to seek medical care if their condition worsens.
Use UPNEEQ with caution in patients with cerebral or coronary insufficiency or Sjögren’s syndrome. Advise patients to seek medical care if signs and symptoms of potentiation of vascular insufficiency develop.
UPNEEQ may increase the risk of angle closure glaucoma in patients with untreated narrow-angle glaucoma. Advise patients to seek immediate medical care if signs and symptoms of acute narrow-angle glaucoma develop.
Patients should not touch the tip of the single patient-use container to their eye or to any surface, in order to avoid eye injury or contamination of the solution.

ADVERSE REACTIONS

Adverse reactions that occurred in 1-5% of subjects treated with UPNEEQ were punctate keratitis, conjunctival hyperemia, dry eye, blurred vision, instillation site pain, eye irritation and headache.

DRUG INTERACTIONS

Alpha-adrenergic agonists, as a class, may impact blood pressure. Caution in using drugs such as beta blockers, anti-hypertensives, and/or cardiac glycosides is advised. Caution should also be exercised in patients receiving alpha adrenergic receptor antagonists such as in the treatment of cardiovascular disease, or benign prostatic hypertrophy.
Caution is advised in patients taking monoamine oxidase inhibitors which can affect the metabolism and uptake of circulating amines.

To report SUSPECTED ADVERSE REACTIONS or product complaints, contact RVL Pharmaceuticals at 1-877-482-3788. You may also report SUSPECTED ADVERSE REACTIONS to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Reference: 1. Upneeq ^® (oxymetazoline hydrochloride ophthalmic solution), 0.1%. [Prescribing Information]. RVL Pharmaceuticals, Inc. 2020.

*Required Information
Please enter your first name
Please enter your last name
Please enter your practice name
Please enter your e-mail address
Please enter your ZIP
Please enter your phone number
Question This form is not intended for the reporting of adverse events or product complaints associated with the use of prescription drugs. For medical information or to report adverse events/product complaints, please email us at MedicalInfo@rvlpharma.com or call 877-482-3788.
* Specialty Please select specialty

Getting Your Patient
Started With Upneeq ^®
(oxymetazoline hydrochloride ophthalmic solution), 0.1%

Simple, once-daily dosing ¹

Modernizing prescription access

Prescribing Upneeq

844-RVL-EYES

(844-785-3937)

For more information about the location and hours for RVL Pharmacy, click here.

ePrescribe

HCP FAQs

How do I prescribe Upneeq?

ePrescribe

How is Upneeq supplied?

I have prescribed Upneeq to my patient. What’s next?

How can my patients pay for Upneeq?

Does RVL Pharmacy accept insurance? What is the cost of Upneeq to my patient?

How and when will my patient receive Upneeq?

How do I prescribe refills of Upneeq to my patients?

What are the storage requirements for Upneeq?

RVL Pharmacy Resources for HCPs

ABOUT
ACQUIRED
BLEPHAROPTOSIS

WHAT UPNEEQ
OFFERS YOUR
PATIENTS

RESOURCE
LIBRARY AND
FIND-A-SPECIALIST

Getting Your Patient Started With Upneeq ® (oxymetazoline hydrochloride ophthalmic solution), 0.1%

Simple, once-daily dosing 1

Modernizing prescription access

Prescribing Upneeq

844-RVL-EYES (844-785-3937)

ePrescribe

HCP FAQs

ePrescribe

RVL Pharmacy Resources for HCPs

ABOUT ACQUIRED BLEPHAROPTOSIS

WHAT UPNEEQ OFFERS YOUR PATIENTS

RESOURCE LIBRARY AND FIND-A-SPECIALIST

INDICATION

IMPORTANT SAFETY INFORMATION

WARNINGS AND PRECAUTIONS

ADVERSE REACTIONS

DRUG INTERACTIONS

Getting Your Patient
Started With Upneeq ^®
(oxymetazoline hydrochloride ophthalmic solution), 0.1%

Simple, once-daily dosing ¹

844-RVL-EYES

(844-785-3937)

ABOUT
ACQUIRED
BLEPHAROPTOSIS

WHAT UPNEEQ
OFFERS YOUR
PATIENTS

RESOURCE
LIBRARY AND
FIND-A-SPECIALIST